Two sample MR report
LGALS2_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0283213 | 0.2479720 | 0.9195023 |
| Weighted median | 4 | 0.0373828 | 0.0146030 | 0.0104691 |
| Inverse variance weighted | 4 | 0.0378773 | 0.0127369 | 0.0029412 |
| Simple mode | 4 | 0.0370173 | 0.0183513 | 0.1370335 |
| Weighted mode | 4 | 0.0369077 | 0.0190443 | 0.1480024 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1190873 | 2 | 0.9421944 |
| Inverse variance weighted | 0.1205763 | 3 | 0.9892587 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0046247 | 0.1198482 | 0.9727245 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.49e-05 | 0 | TRUE | 0.5762936 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
